NCT05601037

LymphoVenous Anastomosis to Prevent Breast Cancer Related Lymphedema

Lymfo-Veneuse Anastomosen Ter Preventie Van Lymphoedeem

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: University Hospital, Ghent · Academic / Other
• Sex: Female
• Age: 18 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

Lymphedema is defined as a chronic condition, caused by lymphostasis. A major part in the Western world consists of iatrogenic lymphedema caused by surgery to the lymph nodes of the axilla or groin. Prophylactic lymphovenous anastomosis (LVA) could be beneficial in the prevention of lymphedema of the extremities.

Detailed description

The investigator is performing a blinded randomized prospective study on 80 patients undergoing an axilla dissection for their breast cancer treatment. One group will receive a LVA at the time of their axilla dissection. Other group will receive standard of care. Follow-up is 2 year.

Conditions

• Lymphedema, Breast Cancer

Interventions

Type	Name	Description
PROCEDURE	Axilla dissection + Lymphovenous anastomosis	surgical bypass between lymphatic vessel and vein

Timeline

• Start date: 2021-06-30
• Primary completion: 2025-12-27
• Completion: 2026-12-27
• First posted: 2022-11-01
• Last updated: 2024-11-08

Locations

1 site across 1 country: Belgium