NCT05597774

Effects of Respiratory Muscle Training in Individuals With Long-term Post-COVID-19 Symptoms

Effects of Respiratory Muscle Training Combined With an Exercise Training Program in Individuals With Long-term Post-COVID-19 Symptoms

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 64 (actual)
• Sponsor: Universidad Complutense de Madrid · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

The main objective of the present study is to observe the short-term effects of respiratory muscle training combined with an exercise training program on quality of life and exercise tolerance in individuals with long-term post-COVID-19 symptoms. As secondary objectives, the effects on respiratory muscle function, physical and lung function, as well as on the psychological state of these individuals.

Detailed description

It is a double-blind randomized clinical trial study. Each participant will be randomly assigned to one of the following groups: 1) Exercise training program + Inspiratory muscle training + Expiratory muscle training, 2) Exercise training program + Sham Inspiratory muscle training + Sham Expiratory muscle training. The exercise training program will be delivered in hospital and will be applied 2 sessions per week during 8 weeks. The exercise component will be lasted for 1hour and it consisted of cardiovascular exercises. The respiratory muscle training program will be applied twice a day, 3 sessions per week during 8 weeks by a threshold device. The evening sessions will be supervised by a physiotherapist through a virtual platform. Participants received baseline assessments at the beginning of the intervention and post-intervention assessments at the end of the 8th week.

Conditions

• Covid19
• Post-acute COVID-19 Syndrome

Interventions

Type	Name	Description
OTHER	Inspiratory + expiratory muscle training group	Participants will perform an inspiratory and expiratory muscle training including warm-up, recovery between intervals and return to calm.
OTHER	Inspiratory + expiratory muscle training sham group	Participants will perform an inspiratory and expiratory muscle training including warm-up, recovery between intervals and return to calm.
OTHER	Exercise training program	Participants will perform a cardiovascular exercise program including warm-up, recovery between intervals and return to calm by cycloergometer.

Timeline

• Start date: 2022-10-28
• Primary completion: 2023-09-22
• Completion: 2023-09-22
• First posted: 2022-10-28
• Last updated: 2023-09-28

Locations

1 site across 1 country: Spain