NCT05596331

Social Information Processing in Children: an ocUlo-pupillometric Tool for Standard Evaluation

SIRCUS : Social Information pRocessing in Children:an ocUlo-pupillometric Tool for Standard Evaluation

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 460 (estimated)
• Sponsor: University Hospital, Tours · Academic / Other
• Sex: All
• Age: 1 Day – 50 Years
• Healthy volunteers: Accepted

Summary

The goal of this observational study is to identify behavioral and physiological markers of social alterations in Autism Spectrum Disorders compared to Typically Developping peers. This single-centre study plan to use eye tracking to evaluate social disorders in Autism Spectrum Disorders (ASD). The investigators will estimate oculometric and pupillometric indices as potential ASD biomarkers. The study will last 4 years and will be organized in two phases.

Detailed description

In a first phase (expected to last 12-16 months), after an experimental validation in typical adults, relevant oculometric and pupillometric indices will be identified in a typical population of children and in a clinically diagnosed population of ASD children. In a second phase of the protocol (expected to last 32-36 months), biomarkers identified in the first phase will be tested on a larger population including other neurodevelopmental disorders.

Conditions

• Autism Spectrum Disorder

Interventions

Type	Name	Description
OTHER	eye-tracker	Eye-tracker recordings of eye movements, gaze direction and pupillary reactivity

Timeline

• Start date: 2023-01-03
• Primary completion: 2026-01-03
• Completion: 2026-09-01
• First posted: 2022-10-27
• Last updated: 2023-12-05

Locations

1 site across 1 country: France