NCT05595135

Mobile Intervention to Improve Adherence of Oral Anti-cancer Medications Among Acute Myeloid Leukemia Patients, the txt4AML Study

txt4AML: An Innovative Mobile Intervention to Improve Oral Anti-Cancer Medications Among Acute Myeloid Leukemia Patients

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Thomas Jefferson University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This clinical trial studies how well a mobile intervention consisting of a text messaging program and an electronic "smart" pill bottle with medication reminders works to improve adherence to oral anti-cancer medications among patients with acute myeloid leukemia (AML). Medication adherence is how well patients take medications as prescribed by their doctors, and good medical adherence is when patients take medications correctly. Poor medication adherence has been shown to be a barrier to effective treatment. Collecting feedback on patient experiences using the mobile intervention may help doctors design new methods and material for providing educational information to AML patients who are taking oral anti-cancer medications.

Detailed description

PRIMARY OBJECTIVE: I. To examine the feasibility, acceptability and preliminary efficacy of txt4AML in a pilot single arm study. SECONDARY OBJECTIVE: I. To explore the association between overall treatment responses and real-time oral anti-cancer medication (OAM) adherence. EXPLORATORY OBJECTIVE: I. To summarize and assess other patient-reported outcomes, collected either as patient chart review or through self-reported survey, as well as the patient post-intervention interviews. OUTLINE: Patients receive interactive text messages to help with adherence to medications and a smart pill bottle with medication reminders on study.

Conditions

• Acute Myeloid Leukemia

Interventions

Type	Name	Description
OTHER	Text Message-Based Navigation Intervention	Receive interactive text messaging.
OTHER	Behavioral, Psychological or Informational Intervention	Receive medication reminders via smart pill bottle
OTHER	Survey Administration	Ancillary studies
OTHER	Quality-of-Life Assessment	Ancillary studies

Timeline

• Start date: 2022-08-15
• Primary completion: 2023-05-05
• Completion: 2023-05-05
• First posted: 2022-10-26
• Last updated: 2025-04-29

Locations

2 sites across 1 country: United States