NCT05592158

Evaluation of the Effectiveness of an Amnion-chorion Membrane for Alveolar Ridge Preservation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: University of Michigan · Academic / Other
• Sex: All
• Age: 20 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This study will examine whether adding an amnion-chorion membrane on top of the traditionally used collagen plug will lead to more bone formation compared to the collagen plug only.

Detailed description

Bone grafts and membranes are commonly placed to increase the amount of bone right after tooth extraction and before placing a dental implant. The primary objective of this study is to study the effect of a human amnion-chorion membrane (ACM) in an exposed-barrier ridge preservation technique to a control group without utilizing a ACM. 30 patients requiring a front tooth extraction will be recruited and randomized to receive bone grafting with or without an ACM.

Conditions

• Healing Wound

Interventions

Type	Name	Description
PROCEDURE	Socket preservation	After tooth extraction, the socket will be filled with a collagen plug and covered with an amnion-chorion membrane.

Timeline

• Start date: 2022-11-16
• Primary completion: 2025-02-14
• Completion: 2025-02-14
• First posted: 2022-10-24
• Last updated: 2025-03-25

Locations

1 site across 1 country: United States