Trials / Completed
CompletedNCT05591417
Dexmedetomidine vs Dexamethasone as Adjuvant to Bupivacaine in Bilevel Erector Spinae Plane Block in Breast Surgeries
Comparison of Dexmedetomidine and Dexamethasone as Adjuvant to Bupivacaine in Ultrasound-guided Bilevel Erector Spinae Plane Block in Modified Radical Mastectomy
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 68 (actual)
- Sponsor
- National Cancer Institute, Egypt · Academic / Other
- Sex
- Female
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
High percent of patients experience chronic pain following breast cancer surgeries thus proper perioperative pain control is crucial to lessen the incidence of such pain. Several techniques are adopted to control perioperative pain, these techniques include drugs as opioids and adjuvants as well as regional blocks. Erector spinae plane block is a regional technique that is used efficiently to control perioperative pain during and following breast cancer surgeries.
Detailed description
High percent of patients experience chronic pain following breast cancer surgeries thus proper perioperative pain control is crucial to lessen the incidence of such pain. Several techniques are adopted to control perioperative pain, these techniques include drugs as opioids and adjuvants as well as regional blocks. Erector spinae plane block is a regional technique that is used efficiently to control perioperative pain during and following breast cancer surgeries. Adding adjuvant drugs as dexmedetomidine or dexamethasone can augment the local anesthetic effect for the regional block used.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Bilevel Erector spinae plane block | Patients will receive bilevel erector spinae plane block with bupivacaine |
| PROCEDURE | Bilateral Erector spinae plane block with dexamethasone | Patients will receive bilevel erector spinae plane block with bupivacaine and dexamethasone |
| PROCEDURE | Bilateral Erector spinae plane block with dexmedetomidine | Patients will receive bilevel erector spinae plane block with bupivacaine and dexmedetomidine |
| DRUG | Intravenous morphine | Intravenous morphine 0.1 mg/kg |
Timeline
- Start date
- 2022-10-27
- Primary completion
- 2024-09-25
- Completion
- 2024-09-30
- First posted
- 2022-10-24
- Last updated
- 2024-10-29
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT05591417. Inclusion in this directory is not an endorsement.