Clinical Trials Directory

Trials / Completed

CompletedNCT05591079

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of CS0159 in Subjects With NASH

A Phase II, Randomized, Double-blind, Placebo-controlled Multicenter Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of CS0159 in the Treatment of Patients With Nonalcoholic Steatohepatitis (NASH)

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
99 (actual)
Sponsor
Cascade Pharmaceuticals, Inc · Academic / Other
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

A randomized, double-blind study to assess the safety, tolerability, PK and efficacy of CS0159 in subjects with Non-Alcoholic Steatohepatitis (NASH)

Detailed description

This will be a multicenter, double-blind, randomized, placebo-controlled, dose-ranging study to evaluate the safety, tolerability, PKs, and efficacy of CS0159 in the treatment of patients with NASH over 12 weeks.

Conditions

Interventions

TypeNameDescription
DRUGCS0159 (Linafexor)Oral QD

Timeline

Start date
2023-02-10
Primary completion
2023-11-09
Completion
2023-11-09
First posted
2022-10-24
Last updated
2023-11-21

Locations

17 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05591079. Inclusion in this directory is not an endorsement.

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of CS0159 in Subjects With NASH (NCT05591079) · Clinical Trials Directory