NCT05587400

Consistency of Electrical Cardiometry and Pulmonary Artery Catheter

The Consistency of Cardiac Output Measured by Electrical Cardiometry and Pulmonary Artery Catheter in Cardiac Surgery Patients With Pulmonary Arterial Hypertension or Right Heart Dysfunction

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 199 (estimated)
• Sponsor: Shanghai Zhongshan Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Currently, the gold standard method to estimate CO in patients with PAH or RV dysfunction is pulmonary artery catheter (PAC), however, the invasiveness and complexity of PAC has limited its usefulness in many clinical scenarios. By measuring the thoracic electrical bioimpedance, electrical cardiometry (EC) technique has been reported to noninvasively estimate cardiac output (CO) and other parameters related to cardiac contractility and fluid status in various cardiovascular disorders. However, in patients with pulmonary arterial hypertension (PAH) and/or right ventricular (RV) dysfunction, few study has been reported. The aim of this study is to evaluate the agreement between CO measured by PAC as the referenced method and CO measured by EC technique in patients with PAH and/or RV dysfunction.

Conditions

• Pulmonary Arterial Hypertension
• Right Ventricular Dysfunction

Interventions

Type	Name	Description
BEHAVIORAL	passive leg raising	transfer a patient from semi-recumbent position to supine position with a 45° leg lifting
DRUG	dobutamine test	infusion dobutamine
DRUG	inhaled nitric oxide	nitric oxide inhalation

Timeline

• Start date: 2022-07-27
• Primary completion: 2024-12-31
• Completion: 2024-12-31
• First posted: 2022-10-20
• Last updated: 2022-10-20

Locations

1 site across 1 country: China