NCT05587153

Perfusion Index vs Positional Hemodynamic Changes to Predict Hypotension After Spinal Anaesthesia in Caesarean Section

Comparative Study Between the Perfusion Index and Positional Haemodynamic Changes for Prediction of Hypotension After Spinal Anaesthesia in Caesarean Section

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 80 (estimated)
• Sponsor: Zagazig University · Other Government
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

Comparative Study between the Perfusion Index and Positional Haemodynamic Changes for Prediction of Hypotension after Spinal Anaesthesia in Caesarean Section

Detailed description

Hypotension following spinal anaesthesia may cause maternal dizziness, nausea, vomiting and fetal acidosis, administration of prophylactic vasopressor agents in pregnant women may cause undesirable effects on the mother and fetus. Perfusion index is the ratio of a pulsatile to a non-pulsatile fraction of blood volume. The increase of the pulsatile fraction manifested during vasodilatation corresponds to a higher PI. So, the patients with a higher PI have a higher risk for post-spinal hypotension. Elevated sympathetic activity before neuraxial anaesthesia was associated with a higher risk for post-spinal hypotension. The significant variability in haemodynamic after the positional change indicates higher sympathetic activity. The high the rise in autonomic activity, the higher the risk for post-spinal hypotension AIM OF THE WORK: Prediction of hypotension after spinal anaesthesia in caesarean section either by perfusion index and positional haemodynamic changes Grouping: All the recruited patients will be assessed by perfusion index. and by positional haemodynamic changes

Conditions

• Post Spinal Hypotension

Interventions

Type	Name	Description
OTHER	perfusion index in all parturient recruited for the study	Using perfusion index and positional hemodynamic changes for the prediction of postspinal hypotension in all parturient recruited for the study

Timeline

• Start date: 2022-07-15
• Primary completion: 2022-12-30
• Completion: 2022-12-30
• First posted: 2022-10-19
• Last updated: 2022-12-23

Locations

2 sites across 1 country: Egypt