NCT05585177

Growth Hormone to Improve the Clinical Outcome of Assisted Fertility in Young Patients With Decreased Ovarian Reserve

A Randomized Controlled Trial of Growth Hormone to Improve the Clinical Outcome of Assisted Fertility in Young Patients With Decreased Ovarian Reserve

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (estimated)
• Sponsor: Nanjing University · Academic / Other
• Sex: Female
• Age: 20 Years – 34 Years
• Healthy volunteers: Not accepted

Summary

This study was a prospective randomized controlled trial. Patients aged \<35 years with decreased clinical reserve function (AFC\<5, Follicle stimulating hormone \> 10miu/ml, Anti-mullerian hormone \< 1.1μg/L) and receiving IVF/ICSI assisted ovulation induction in our hospital were included in this study. After randomization using Excel(Microsoft Corporation, Albuquerque, USA), these patients were divided into two groups. Group A was the experimental group, which was treated with growth hormone for 3 months (2 units per day) before IVF/ICSI. Group B was the control group, which was directly assisted by IVF/ICSI.

Conditions

• Infertility

Interventions

Type	Name	Description
DRUG	Growth hormone	3 months of growth hormone treatment (2 units daily)

Timeline

• Start date: 2022-11-01
• Primary completion: 2024-11-30
• Completion: 2025-10-30
• First posted: 2022-10-18
• Last updated: 2022-10-24

Locations

1 site across 1 country: China