NCT05584943

Kinetics of cEVs Over the 24-hour Dosing Interval After Low-dose Aspirin Administration

Kinetics of Circulating Extracellular Vesicles Over the 24-hour Dosing Interval After Low-dose Aspirin Administration in Patients at Cardiovascular Risk

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 93 (actual)
• Sponsor: G. d'Annunzio University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

Extracellular vesicles (EVs) are small vesicles deriving from all cell types during cell activation, involved in transcellular communication, and regarded as predictors of vascular damage and of cardiovascular events. The investigators will test the hypothesis that, in patients on chronic low-dose aspirin treatment for cardiovascular prevention, aspirin may affect the release of EVs within the 24 hours interval.

Conditions

• Cardiovascular Diseases
• Vesicle

Timeline

• Start date: 2015-09-21
• Primary completion: 2017-05-09
• Completion: 2017-12-31
• First posted: 2022-10-18
• Last updated: 2022-10-18