NCT05584124

rTMS for Post-stroke Fatigue

Neuromodulation for Rehabilitation of Post-Stroke Fatigue: An rTMS Pilot Study

• Status: Suspended
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: VA Office of Research and Development · Federal
• Sex: All
• Age: 35 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This experimental trial is investigating the use of magnetic stimulation of the brain as a possible treatment for people with post-stroke fatigue. Fatigue is a common condition after a stroke and can negatively impact an individual's ability to perform desired social and physical activities. Magnetic stimulation of the brain has been shown to improve signs and symptoms of related psychological (e.g., depression) conditions. Participants in this trial will receive a type of magnetic stimulation called repetitive magnetic stimulation, or rTMS. The investigators will measure feelings of fatigue, and other clinical characteristics related to mood and cognition, before and after participants receive rTMS.

Conditions

• Stroke
• Stroke, Chronic
• Fatigue

Interventions

Type	Name	Description
DEVICE	High frequency repetitive transcranial magnetic stimulation	MAGSTIM Super Rapid2 Plus
DEVICE	Sham repetitive transcranial magnetic stimulation	MAGSTIM Super Rapid2 Plus

Timeline

• Start date: 2023-04-10
• Primary completion: 2027-10-29
• Completion: 2027-10-29
• First posted: 2022-10-18
• Last updated: 2025-11-03

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study