NCT05583539

Thromboelastography Guided Blood Product Transfusion for Upper Gastrointestinal Bleeding in Cirrhosis

A Pilot Study of Thromboelastography Guided Blood Product Transfusion for Patient With Cirrhosis and Upper Gastrointestinal Bleeding

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Vanderbilt University Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to compare resuscitation strategies in patients with cirrhosis and gastrointestinal bleeding. The main question it aims to answer is whether thromboelastography guided resuscitation decreased the amount of fresh frozen plasma patients receive. Patients will receive blood products guided by thromboelastography in the intervention group. Researchers will compare the patients who undergo thromboelastography guided resuscitation to those who receive usual care to see which strategy leads to the use of less blood products, specifically less fresh frozen plasma.

Conditions

• Cirrhosis, Liver
• Coagulopathy
• GastroIntestinal Bleeding

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Thromboelastography	Thromboelastography is a viscoelastic test that measures the dynamics of blood clotting on whole blood samples.

Timeline

• Start date: 2025-01-16
• Primary completion: 2025-06-15
• Completion: 2025-06-30
• First posted: 2022-10-17
• Last updated: 2024-04-12

Regulatory

• FDA-regulated device study