NCT05583136

Restoring Neural Oscillatory Communication in Developmental Dyslexia

Restoring Neural Oscillatory Communication Between Dorsal and Ventral Visual Streams in Developmental Dyslexia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 78 (actual)
• Sponsor: IRCCS Ospedale San Raffaele · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

Developmental dyslexia (DD) is a multifactorial disorder that hampers the education of about 10% of individuals across cultures and is associated to both phonological and visual deficits. The latter have been linked to a deficit in the magnocellular-dorsal (M-D) visual stream, that has a critical role in guiding the activity of ventral visual stream areas where letters identity is extracted. Here, we will test the efficacy of transcranial alternate current stimulation (tACS) of the M-D stream combined with reading trainings in adult participants with DD, assessing the neurophysiological underpinnings of these new trainings with EEG and fMRI/DTI.

Conditions

• Developmental Dyslexia

Interventions

Type	Name	Description
DEVICE	Parietal tACS combined with visuo-attentional training	Parietal tACS combined with visuo-attentional training
DEVICE	Sham (placebo) tACS combined with visuo-attentional training	Sham (placebo) tACS combined with visuo-attentional training
DEVICE	Sham (placebo) tACS combined with phonics training	Sham (placebo) tACS combined with phonics training

Timeline

• Start date: 2021-12-14
• Primary completion: 2024-12-23
• Completion: 2024-12-23
• First posted: 2022-10-17
• Last updated: 2025-01-27

Locations

1 site across 1 country: Italy