NCT05579795

Surgical Management and Outcome of Tethered Cord Syndrome

Tethered Cord Syndrome: Surgical Management and Outcome

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 35 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 1 Year – 16 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to assess surgical management and outcome of Tethered cord syndrome

Detailed description

Tethered cord syndrome (TCS) is a developmental abnormality of the neuroaxis which is usually diagnosed in childhood. The actual tethering has been attributed to a variety of pathologic entities, including a thickened tight filum terminale , intradural lipomas with or without a connecting extradural component, intradural fibrous adhesions, diastematomyelia, and adherence of the neural placode following previous closure of a myelomeningocele. However, sufficient differences in the mode of onset, clinical manifestations, and outcome exist between pediatric and adolescent patients with tethered cord to warrant a more detailed analysis of the adult syndrome. The most problematic technical consideration in surgery for the release of the tethered cord is how to preserve functioning neural elements and rebuild the dural sac to avoid CSF leak. The purpose of this study is to review causes of Tethered cord, clinical presentation, diagnostic tools, treatment options and outcome in school-aged children, adolescents, and young adults with Tethered cord.

Conditions

• Tethered Cord Syndrome

Interventions

Type	Name	Description
PROCEDURE	Detethering of the spinal cord	Release of the tethered spinal cord

Timeline

• Start date: 2022-11-02
• Primary completion: 2024-11-02
• Completion: 2024-12-02
• First posted: 2022-10-14
• Last updated: 2022-11-03