NCT05578404

High Oral Loading Dose of Cholecalciferol in Non-Alcoholic Fatty Liver Disease

The Effect of High Oral Loading Dose of Cholecalciferol in Non-Alcoholic Fatty Liver Disease Patients

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Tanta University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Non-alcoholic fatty liver disease (NAFLD) is a metabolic disorder with high prevalence in patients suffering from chronic liver diseases \[1\]. NAFLD is characterized by the accumulation of \> 5% of fat deposits in hepatocytes (hepatic steatosis) with no known other reasons for steatosis as excessive alcohol intake.The global prevalence of NAFLD differs depending on the population reaching 13% in Africa, 32% in the Middle East, and 30 % in the United States

Conditions

• Non-Alcoholic Fatty Liver Disease

Interventions

Type	Name	Description
DRUG	Cholecalciferol	Vit D is a fat-soluble vitamin, provided by sunlight and activated by kidneys and liver.
DRUG	Placebo	matching placebo to Vit D

Timeline

• Start date: 2022-10-20
• Primary completion: 2023-04-20
• Completion: 2023-04-20
• First posted: 2022-10-13
• Last updated: 2023-11-29

Locations

1 site across 1 country: Egypt