NCT05576948

Natural History of Cerebral Palsy Prospective Study

Understanding the Early Natural History of Cerebral Palsy - A Prospective Cohort Study

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Children's Hospital Medical Center, Cincinnati · Academic / Other
• Sex: All
• Age: 3 Months – 24 Months
• Healthy volunteers: —

Summary

The study will describe the natural history of cerebral palsy (CP) as children develop over the first 2 years of life.

Detailed description

This study aims to describe the early natural history of cerebral palsy (CP) by mapping the development of infants with, or at-risk of CP, over the first two years of life. Infants will be assessed at regular intervals up to 24 months of age, across a variety of childhood development to provide the first comprehensive developmental trajectories of this group. In doing so, it will contribute to the existing knowledge of CP development to assist clinicians and therapists with accurate information on prognosis and provide targeted interventions early and at the 'just-right' challenge. Where indicated, individual participants' results from this study will be used to inform their therapy. This study is intended to form part of a larger multi-site international study.

Conditions

• Cerebral Palsy

Timeline

• Start date: 2022-09-08
• Primary completion: 2026-09-08
• Completion: 2027-09-08
• First posted: 2022-10-13
• Last updated: 2025-09-25

Locations

1 site across 1 country: United States