Trials / Completed
CompletedNCT05575297
A Drug-drug Interaction Study to Evaluate the Effect of Rifampicin and Febuxostat on the Pharmacokinetics of Methotrexate in Healthy Subjects
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 12 (actual)
- Sponsor
- Seoul National University Hospital · Academic / Other
- Sex
- Male
- Age
- 19 Years – 45 Years
- Healthy volunteers
- Accepted
Summary
To investigate the effect of rifampicin and febuxostat on pharmacokinetics of methotrexate in healthy volunteers
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Methotrexate Sodium | Methotrexate oral administration alone |
| DRUG | Rifampicin Sodium | Co-administration of methotrexate and rifampicin |
| DRUG | Febuxostat Tablets | Co-administration of methotrexate and febuxostat |
Timeline
- Start date
- 2021-12-20
- Primary completion
- 2022-05-03
- Completion
- 2022-05-09
- First posted
- 2022-10-12
- Last updated
- 2022-10-12
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT05575297. Inclusion in this directory is not an endorsement.