NCT05574153

Metabolic Risk Factors and Myocardial Oxygenation Reserve

Metabolic Risk Factors and Myocardial Oxygenation Reserve (META-MORE)

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 75 (estimated)
• Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to use MRI images using the OS-CMR technique to view the differences in the hearts of healthy volunteers and participants with a condition called Metabolic Syndrome. The objectives of this project are to compare these two groups and to view how health risks, blood test results, and the time since a Metabolic diagnosis can affect heart health.

Detailed description

Myocardial oxygenation changes during vasoactive breathing maneuvers, observed with oxygenation-sensitive cardiac MRI, will be identified and compared between individuals considered healthy and those fitting the criteria of the Metabolic Syndrome.

Conditions

• Metabolic Syndrome

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Cardiac MRI	Participants will undergo an oxygenation-sensitive cardiac MRI and, during the scan, perform a vasoactive breathing maneuver composed of a period of paced hyperventilation followed by a voluntary maximal breath hold.

Timeline

• Start date: 2021-06-30
• Primary completion: 2024-12-30
• Completion: 2024-12-30
• First posted: 2022-10-10
• Last updated: 2024-10-24

Locations

1 site across 1 country: Canada