NCT05567133

Risk Indicators of Sarcoidosis Evolution-Unified Protocol

Development of Clinical Prediction Models for Pulmonary Outcomes in Sarcoidosis

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: University of California, San Francisco · Academic / Other
• Sex: All
• Age: 19 Years
• Healthy volunteers: —

Summary

The purpose of this study is to develop prediction models that can prognosticate patients with sarcoidosis using clinical data and blood markers that can be obtained during a clinic visit.

Detailed description

The purpose of this study is to develop prediction models that can prognosticate patients with sarcoidosis using clinical data and biological markers that can be obtained during a clinic visit. Primary Aim/Objective The primary objective of this study is to determine which clinical features measured during a routine clinic visit are risk factors for progression of pulmonary sarcoidosis over the follow-up period in adults with pulmonary sarcoidosis. Secondary Aim/Objectives The secondary objective is to determine if blood biomarkers measured during a routine clinic visit can improve the risk assessment for progression of pulmonary sarcoidosis over the follow-up period. The investigators will measure two types of blood markers to achieve this goal: * Clinically available blood markers that are available in most clinical labs * Blood proteins and gene expression that reflect interferon inflammation and are not currently available as tests in clinical labs

Conditions

• Sarcoidosis, Pulmonary

Timeline

• Start date: 2023-01-10
• Primary completion: 2030-03-30
• Completion: 2030-03-30
• First posted: 2022-10-05
• Last updated: 2026-01-08

Locations

2 sites across 1 country: United States