Clinical Trials Directory

Trials / Terminated

TerminatedNCT05565092

Safety, Efficacy, Pharmacokinetic, and Pharmacodynamic Study of ALXN1820 in Adult Participants With Sickle Cell Disease

A Phase 2a, Randomized, Open-Label Study to Evaluate Multiple Dosing Regimens of Subcutaneous ALXN1820 in Adult Participants With Sickle Cell Disease

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
2 (actual)
Sponsor
Alexion Pharmaceuticals, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The primary objective of this study is to assess the safety and tolerability of ALXN1820 SC (subcutaneous) in participants with SCD (Sickle Cell Disease).

Conditions

Interventions

TypeNameDescription
DRUGALXN1820ALXN1820 will be administered subcutaneously.

Timeline

Start date
2023-02-22
Primary completion
2024-01-09
Completion
2024-01-09
First posted
2022-10-04
Last updated
2025-01-13
Results posted
2025-01-13

Locations

2 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05565092. Inclusion in this directory is not an endorsement.

Safety, Efficacy, Pharmacokinetic, and Pharmacodynamic Study of ALXN1820 in Adult Participants With Sickle Cell Disease (NCT05565092) · Clinical Trials Directory