Trials / Completed
CompletedNCT05562856
Clinical Evaluation of White Spot Lesions Treated by S-PRG Material and Composite Sealants in Comparison With ICON
Clinical Evaluation of White Spot Lesions Treated by Surface Pre-reacted Glass Filler Coating Material and Composite Sealants in Comparison With Icon Resin Infiltration by Using Laser Fluorescence and Spectrophotometer
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 20 (actual)
- Sponsor
- Al-Azhar University · Academic / Other
- Sex
- All
- Age
- 20 Years – 40 Years
- Healthy volunteers
- Not accepted
Summary
Dental caries is the primary cause of tooth loss and oral diseases. Dental decay is a continuous pathological process with loss of tooth minerals, demineralization, which involves the destruction of tooth structure from acids. The first sign of early active demineralization is white spot lesions (WSLs) on the tooth surface, meanwhile, subsurface active mineral decomposition.
Detailed description
Deposition of minerals depends on the equilibrium between demineralization and remineralization which may happen as a natural repair mechanism. The aim of this trial is to comparatively evaluate the efficacy of surface pre-reacted glass filler (S-PRG) Barrier Coat coating material against the Icon resin infiltration in the ability to improve the caries lesion state of the WSLs along 1 year. Laser fluorescence was used to compare the two materials to evaluate the caries progression. PRG Barrier Coat group showed immediate significant improvement in LF scores in demineralization progress and inhibition of caries progression with a significant improved effect. S-PRG Barrier Coat was clinically successful strategy in inhibition of caries and improve remineralization.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| COMBINATION_PRODUCT | surface pre-reacted glass filler coating material | the ability to improve the aesthetic appearance (masking) and caries lesion state of the WSLs |
Timeline
- Start date
- 2020-01-20
- Primary completion
- 2021-12-02
- Completion
- 2021-12-03
- First posted
- 2022-10-03
- Last updated
- 2022-10-04
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT05562856. Inclusion in this directory is not an endorsement.