NCT05560529

Dialectical Behavioral Therapy As A Therapeutic Tool In Patients With Binge Eating Disorder

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Alexandria University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Binge eating disorder (BED) is one of the recently acknowledged eating disorders, with many theories underlying its pathology whether biological or psychological. From the biological perspective, changes in plasma ghrelin were hypothesized to have a major role in developing and maintaining the disorder, while from the psychopathological perspectives, abnormalities in emotion regulation were found in many patients. Since Dialectical Behavioral Therapy (DBT) is known to target emotion dysregulation, the main aim of this study is to assess the efficacy of DBT versus treatment as usual (TAU) in BED patients, and whether plasma ghrelin level will be affected after treatment in both arms.

Detailed description

Binge eating disorder (BED) is one of the recently acknowledged eating disorders, with many theories underlying its pathology whether biological or psychological. From the biological perspective, changes in plasma ghrelin were hypothesized to have a major role in developing and maintaining the disorder, while from the psychopathological perspectives, abnormalities in emotion regulation were found in many patients. Since Dialectical Behavioral Therapy (DBT) is known to target emotion dysregulation, the main aim of this study is to assess the efficacy of DBT versus treatment as usual (TAU) in BED patients, and whether plasma ghrelin level will be affected after treatment in both arms, with patients being randomly allocated in both groups.

Conditions

• Binge Eating Disorder

Interventions

Type	Name	Description
BEHAVIORAL	DBT	Applying DBT modules in group format over 20 weeks
DRUG	TAU	Giving TAU (usual pharmacotherapy in BED) over 20 weeks
DIAGNOSTIC_TEST	Plasma Ghrelin	Measuring fasting plasma ghrelin pre and post treatment in both arms

Timeline

• Start date: 2023-03-15
• Primary completion: 2024-06-15
• Completion: 2024-09-15
• First posted: 2022-09-29
• Last updated: 2025-01-29

Locations

1 site across 1 country: Egypt