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Trials / Active Not Recruiting

Active Not RecruitingNCT05559931

Single and Repeat Doses of DMT in Healthy Subjects

A Double-blind, Randomised, Placebo-controlled Study to Evaluate the Pharmacokinetics, Safety and Pharmacodynamics of Ascending Single and Fixed Repeat Intravenous Doses of DMT in Healthy Subjects

Status
Active Not Recruiting
Phase
Phase 1
Study type
Interventional
Enrollment
60 (estimated)
Sponsor
Algernon Pharmaceuticals · Industry
Sex
All
Age
18 Years – 60 Years
Healthy volunteers
Accepted

Summary

This study aims to assess the safety and tolerability of single ascending, and fixed repeated doses of N,N-Dimethyltryptamine (DMT) in healthy subjects, when given by intravenous (IV) infusion.

Conditions

Interventions

TypeNameDescription
DRUGN,N-DimethyltryptamineIV infusion over 6 hours
DRUGPlaceboPlacebo infusion over 6 hours

Timeline

Start date
2023-01-13
Primary completion
2026-03-01
Completion
2026-03-01
First posted
2022-09-29
Last updated
2025-01-28

Locations

1 site across 1 country: Netherlands

Source: ClinicalTrials.gov record NCT05559931. Inclusion in this directory is not an endorsement.