NCT05558670

Brain Network Characteristics in Patients With Disorders of Consciousness

Assessing Brain Network Characteristics in Patients With Disorders of Consciousness by Simultaneous Trimodal Positron Emission Tomography-Functional Magnetic Resonance Imaging-Electroencephalograph（PET-fMRI-EEG）Imaging

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 40 (estimated)
• Sponsor: Xijing Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Simultaneous measurement of the three modalities, functional magnetic resonance imaging (fMRI), positron emission tomography (PET) and electroencephalography (EEG) was proven to be feasible and advantageous in evaluating brain structural and functional (via fMRI), metabolic (via PET) and electrophysiological (via EEG) signatures simultaneously under the same conditions. Investigators use trimodal PET-fMRI-EEG imaging to explore the characteristics of brain network damage in patients with disorders of consciousness(DOC), assess the trajectory of consciousness recovery in a prospective observational cohort study.

Conditions

• Disorders of Consciousness

Interventions

Type	Name	Description
OTHER	PET-fMRI-EEG	Participants perform PET, fMRI, and EEG simultaneously using a MRI compatible EEG cap

Timeline

• Start date: 2022-09-01
• Primary completion: 2023-04-01
• Completion: 2023-10-01
• First posted: 2022-09-28
• Last updated: 2022-09-28

Locations

1 site across 1 country: China