NCT05556174

Intraoperative Lung Protective Ventilation Needs Periodic Lung Recruitment Maneuvers

Intraoperative Lung Protective Ventilation With or Without Periodic Lung Recruitment Maneuvers on Pulmonary Complications After Major Abdominal Surgery: a Prospective Randomized Controlled Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,060 (actual)
• Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Postoperative Pulmonary Complications (PPC) are common. It severely affects postoperative recovery, particularly in abdominal surgery. Several studies showed that intraoperative lung-protective ventilation with periodic lung recruitment maneuvers could reduce postoperative pulmonary complications. Other studies showed that intraoperative lung protective ventilation without periodic lung recruitment maneuvers could also reduce postoperative pulmonary complications. The purpose of this study was to compare the effects of the above two regimens on postoperative pulmonary complications.

Conditions

• Postoperative Complications
• Abdominal Surgery
• Intraoperative Mechanical Ventilation

Interventions

Type	Name	Description
OTHER	periodic lung recruitment maneuvers	lung recruitment maneuvers repeated every 30 minutes

Timeline

• Start date: 2022-10-09
• Primary completion: 2024-09-11
• Completion: 2024-11-11
• First posted: 2022-09-27
• Last updated: 2025-01-03

Locations

1 site across 1 country: China