Trials / Completed
CompletedNCT05555342
A Novel Method for Treating Lung Met w/Combo of Electric Fields & Rad Therapy: A Single-Arm
A Novel Method for Treating Lung Metastases With the Combination of Electrical Fields and Radiation Therapy: A Single-Arm Pilot Study
- Status
- Completed
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 6 (actual)
- Sponsor
- University of California, Irvine · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This is a phase 0, pilot prospective study to determine the feasibility of combined irreversible electroporation (IRE) and radiation therapy in subjects with lung tumors with metastatic cancer of any histology. These are subjects who have advanced disease (stage IV) or previously treated disease that has become progressive, recurrent, or metastatic.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Irreversible electroporation (IRE) ablation | IRE will be performed using the NanoKnife or Aliya System. CT or cone-beam CT will be used to direct electrode placement. |
| RADIATION | Radiation Therapy | Moderate-dose radiation therapy to the target tumor(s) in 1 fraction. |
Timeline
- Start date
- 2023-01-03
- Primary completion
- 2023-09-29
- Completion
- 2024-10-27
- First posted
- 2022-09-26
- Last updated
- 2025-05-14
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated device study
Source: ClinicalTrials.gov record NCT05555342. Inclusion in this directory is not an endorsement.