Trials / Completed
CompletedNCT05553704
Metformin in Patients With Ulcerative Colitis Treated With Mesalamine
Clinical Study to Compare the Possible Efficacy of Metformin in Patients With Ulcerative Colitis Treated With Mesalamine
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 60 (actual)
- Sponsor
- Tanta University · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disease characterized by diffused inflammation of the colon and rectum mucosa, however, the exact underlying mechanisms of UC remain poorly understood.UC is strongly dependent on cellular immune reaction and exaggerated inflammatory response due to genetic, immune and environmental factors.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Metformin | metformin group will take mesalamine 1 gm three times daily plus metformin 500 mg two times daily |
Timeline
- Start date
- 2022-11-01
- Primary completion
- 2025-03-01
- Completion
- 2025-03-01
- First posted
- 2022-09-23
- Last updated
- 2025-04-08
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT05553704. Inclusion in this directory is not an endorsement.