NCT05553054

Drug Wastage : Observational Study in Intensive Care Units in France

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,066 (actual)
• Sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Environmental awareness leads medical field to question its responsibility and possibilities for action. Drug residues can have a major environmental impact as per their bioaccumulation, toxicity and persistence characteristics, depending on where they are discarded. In France, drug residues should be disposed of by incineration, but in practice, this is not systematic. Moreover, data on drug wastage in Intensive Care Units (ICU) are rare. GAME-OVER observational study aims to evaluate drug wastage in ICU in France and to suggest ways to improve health care practices.

Detailed description

Observational study with data collection during a 24-hour business day. Data collected refer to healthcare team's practices and patients. Collection starts when day shift starts (at 7:00 am) and ends when night shift leaves (at 7:00 am the following day).

Conditions

• Drug Use

Interventions

Type	Name	Description
OTHER	Quantification of IV drugs wastage	Drugs are prescribed depending on physician discretion. Specific collection bins are provided to ICU. Healthcare teams discard syringes labelled with name and dilution which have been used to prepare drugs into these bins. After 24 hours of collection, bins are analyzed by investigators.

Timeline

• Start date: 2022-11-08
• Primary completion: 2023-03-15
• Completion: 2023-03-15
• First posted: 2022-09-23
• Last updated: 2026-04-13

Locations

61 sites across 3 countries: France, Mayotte, Monaco