NCT05547659

Multimodal and Unimodal Analgesia in Cholecystectomy

Comparison Between Multimodal and Unimodal Analgesia in Cholecystectomy

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 95 (actual)
• Sponsor: October 6 University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

Many surgical procedures are accompanied by postoperative pain with severity moderate, severe or extreme and insufficient postoperative pain control may cause risk of post-surgical complications and risk of chronic post-surgical pain The targets of preoperative pain management are to relieve patient suffering, reduce length of hospital stay and achieve early mobilization after surgery, decreasing opioid consumption and its side effects that are constipation, nausea, vomiting, dizziness, respiratory depression which is the most feared complication being life-threatening and some less common side effects as sedation

Conditions

• Compare Unimodal and Multimodal Analgesics

Interventions

Type	Name	Description
DRUG	Pregabalin 150mg	Pregabalin 150mg preoperative in unimodal group Pregabalin 150mg preoperative in multi-modal group
DRUG	Acetaminophen 1 G Oral Tablet	Acetaminophen 1 G Oral Tablet preoperative in multi-modal group
DRUG	Celecoxib 400Mg Oral Capsule	Celecoxib 400Mg Oral Capsule preoperative in multi-modal group

Timeline

• Start date: 2019-01-01
• Primary completion: 2020-04-01
• Completion: 2020-12-01
• First posted: 2022-09-21
• Last updated: 2022-09-21

Locations

2 sites across 1 country: Egypt