NCT05545735

The Duration of Antibiotic Therapy for Early (DATE) Ventilator Associated Pneumonia (VAP): 4 vs. 7 Days

Duration of Antibiotic Therapy for Early (DATE) Ventilator-Associated Pneumonia (VAP) Trial: A Surgical Infection Society Multicenter Randomized Clinical Trial of 4 vs. 7 Days of Definitive Antibiotic Therapy for Early VAP

• Status: Terminated
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 27 (actual)
• Sponsor: University of Miami · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to see if the amount of antibiotics given for ventilator-associated pneumonia (VAP) can be decreased in order to reduce the risk of adverse effects associated with antibiotics, while at the same time ensuring the participant's safety.

Conditions

• Ventilator Associated Pneumonia

Interventions

Type	Name	Description
DRUG	Standard of Care Antibiotic Therapy	Antibiotics will be administered as per the standard of care orally via tablet

Timeline

• Start date: 2023-05-08
• Primary completion: 2025-02-27
• Completion: 2025-02-27
• First posted: 2022-09-19
• Last updated: 2026-01-16
• Results posted: 2026-01-16

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study