NCT05542134

Platelet Agregation in Patients on ECMO

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 50 (estimated)
• Sponsor: University Medical Centre Ljubljana · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

An observational study in which investigators will observe platelet inhibition in patients on VA ECMO acorrding to treatment with P2Y12 inhibitor.

Detailed description

Investigators will perform an observational study in which platelet inhibition in patients on VA ECMO acorrding to treatment with P2Y12 inhibitor will be observed. Participants will be divided into three groups: A: patients on V-A ECMO without P2Y12 inhibitors B patients on V-A ECMO with P2Y12 inhibitors with administration of P2Y12 inhibitor at the time of ECMO insertion C: patients on V-A ECMO already recieving P2Y12 inhibitors at the time of ECMO insertion. Blood samples will be taken prior to and at 2, 4, 12, 22, 48, 72 after ECMO insertion and after removal of an ECMO. VerifyNow System will be used to measure platelet agregation (PRU test).

Conditions

• Platelet Refractoriness

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	P2Y12 Platelet Aggregation Inhibitor	Verify now PRU test

Timeline

• Start date: 2019-01-17
• Primary completion: 2023-06-01
• Completion: 2023-06-01
• First posted: 2022-09-15
• Last updated: 2023-05-12

Locations

1 site across 1 country: Slovenia