NCT05539911

Fentanyl as an Adjuvant to Peribulbar Block in Buckle or Squint Surgeries

The Effect of Using Fentanyl as an Adjuvant to Peribulbar Block to Decrease the Introaoperative Muscle Traction Pain (Proprioception) in Squint and Buckle Surgeries in Adults: RCT

• Status: Unknown
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Research Institute of Ophthalmology, Egypt · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The use of fentanyl as an adjuvant to local anesthetic mixture in many regional blocks. It was effective when used in peribulbar block in cataract and vitreoretinal surgeries. Our study will assess its efficacy in abolishing pain during muscle traction which is usually a complain for many patients a reason to use systemic opioid intra operatively or even general anesthesia

Detailed description

After the patient enters the OR room, an intravenous cannula will be introduced, pulse oximeter, ECG and NIBP monitors will be connected. Nasal oxygen cannula connected; 10 ml of local anesthetic mixture is injected depending on the group the patient is allocated. Increments of intravenous intravenous fentanyl and midazolam will be given if patient experienced unbearable pain. All patient received peribulbar block by an experienced anesthesiologist, both patient and anesthesiologist were blinded to the drug mixture used. Each patient received 10 ml of the anesthetic mixture according to his/ her group. The patient was asked to fix his eyes looking straight forward toward the ceiling while lying in a supine position. A 10 ml syringe with a 25G needle was used for the local anesthetic injection. After negative aspiration, the first 5 ml were slowly injected at the junction of the lateral one third and medial two thirds of the inferior orbital margin with the bevel directed towards the equator of the eye ball parallel to the orbital floor and the other 5 ml were given between the caruncle and the medial canthus. Intermittent gentle massage was applied for 10 minutes. After satisfactory sensory and motor block, oxygen 3 L/min was delivered through a nasal cannula to the patient. Surgery was then allowed to proceed.

Conditions

• Pain

Interventions

Type	Name	Description
DRUG	Fentanyl	50 mic fentanyl added as an adjuvant

Timeline

• Start date: 2022-09-01
• Primary completion: 2022-11-01
• Completion: 2022-11-01
• First posted: 2022-09-14
• Last updated: 2022-10-25

Locations

1 site across 1 country: Egypt