NCT05538741

Hypotension After Anesthetic Induction with Remimazolam in Elderly

Comparison of the Incidence of Hypotension with Bolus Versus Continuous Remimazolam for Anesthetic Induction in Elderly Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 62 (actual)
• Sponsor: Kangbuk Samsung Hospital · Academic / Other
• Sex: All
• Age: 60 Years
• Healthy volunteers: Not accepted

Summary

Even though remimazolam is known to be safely administered without hemodynamic instability, hypotension is the one of the common side effects of remimazolam. Because elderly patients are susceptible to hypotension due to old age, multimodality, and multiple medications, hypotension can be harmful in elderly patients. Remimazolam can be administered either bolus or continuous for anesthetic induction. In our study the investigators aimed to compare the incidence of hypotension after anesthetic induction using remimazolam by bolus injection and continuous infusion in elderly patients.

Conditions

• Hypotension

Interventions

Type	Name	Description
DRUG	Bolus of remimazolam	0.19-0.25 mg/kg for 60-80 years old 0.14-0.19 mg/kg for \>80 years old
DRUG	Continuous infusion of remimazolam	12 mg/kg/hr until loss of consciousness

Timeline

• Start date: 2023-07-14
• Primary completion: 2024-06-14
• Completion: 2024-06-14
• First posted: 2022-09-14
• Last updated: 2024-09-19

Locations

1 site across 1 country: South Korea