NCT05538546

Baveno VI Criteria in Dynamic Monitoring of High-risk Varices in Compensated Cirrhotic Patients

The Value of Baveno VI Criteria for Screening and Monitoring of Varices Needing Treatment in Patients With Compensated Cirrhosis

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: Huashan Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Patients meet Baveno VI criteria (with a liver stiffness \<20kPa and with a platelet count \>150,000 are considered to have very low risk of having varices requiring treatment, but whether these patients can be followed up by repetition of this criteria lacks sufficient evidence. This study aimed to assess the value of Baveno VI criteria for following up and monitoring of varices needing treatment in patients with compensated cirrhosis.

Conditions

• Cirrhosis
• Varices
• Non-invasive Evaluation

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Complete blood count	Complete blood count will be conducted at 12th month and 24th month from baseline.
DIAGNOSTIC_TEST	Transient elastrography	Transient elastrography, and endoscopy will be conducted at 12th month and 24th month from baseline.
DIAGNOSTIC_TEST	Endoscopy	Endoscopy will be conducted at 12th month and 24th month from baseline.

Timeline

• Start date: 2022-09-01
• Primary completion: 2022-12-01
• Completion: 2023-12-01
• First posted: 2022-09-14
• Last updated: 2022-09-14