NCT05538351

A Study to Support the Development of the Enhanced Fluid Assessment Tool for Patients With Acute Kidney Injury

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 120 (estimated)
• Sponsor: University of Hertfordshire · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Acute Kidney Injury (AKI) is the sudden and recent reduction in kidney function. This can be detected by measuring a rise in blood creatinine level or from a reduction in urine. Reasons for developing AKI, include dehydration, low blood pressure, medication and infection. When the kidneys stop working, there can be a build-up of toxins and fluid. It is extremely important to identify a patient's fluid status as too little can cause further damage to the kidneys and too much can be harmful. Assessment is varied and often inaccurate and there needs to be a standard approach to fluid assessment.

Detailed description

Acute Kidney Injury (AKI) is the sudden and recent reduction in kidney function. This can be detected by measuring a rise in blood creatinine level or from a reduction in urine. Reasons for developing AKI, include dehydration, low blood pressure, medication and infection. When the kidneys stop working, there can be a build-up of toxins and fluid. It is extremely important to identify a patient's fluid status as too little can cause further damage to the kidneys and too much can be harmful. Assessment is varied and often inaccurate and there needs to be a standard approach to fluid assessment. Aim: To develop an Enhanced Fluid Assessment Tool for patients with AKI. Workstream 1: Aim: To identify what methods are useful to assess fluid in a patient with AKI. The fluid assessment techniques that are useful and are used, bioimpedance and patient reported signs and symptoms. Workstream 2: Aim: To identify the best methods of determining fluid status in a patient with AKI The findings from Workstream 1 will be used to rank the most useful fluid assessment techniques. This will lead to the development of the enhanced fluid assessment tool. Workstream 3: Aim: To assess if the tool is practical and clinically useful in determining a patient's fluid status. The terminology and language will be reviewed and the tool will be used to assess patients and to determine the patients fluid status.

Conditions

• Acute Kidney Injury

Interventions

Type	Name	Description
DEVICE	Body Composition Monitor (BCM)	The hydration status of each participant from the clinical assessment and the patient reported signs and symptoms will be compared with the readings from bioimpedance (BCM machine).

Timeline

• Start date: 2022-09-09
• Primary completion: 2026-08-01
• Completion: 2026-08-01
• First posted: 2022-09-13
• Last updated: 2025-12-05

Locations

1 site across 1 country: United Kingdom