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RecruitingNCT05536011

WAKIX® (Pitolisant) Pregnancy Registry

WAKIX® (Pitolisant) Pregnancy Registry: An Observational Study of the Safety of Pitolisant Exposure in Pregnant Women and Their Offspring

Status
Recruiting
Phase
Study type
Observational
Enrollment
1,329 (estimated)
Sponsor
Harmony Biosciences Management, Inc. · Industry
Sex
Female
Age
Healthy volunteers
Not accepted

Summary

The WAKIX (pitolisant) Pregnancy Registry is a US-based, prospective, observational cohort study designed to evaluate the association between pitolisant exposure during pregnancy and subsequent maternal, fetal, and infant outcomes.

Detailed description

The WAKIX (pitolisant) Pregnancy Registry is a US-based, prospective, observational cohort study designed to evaluate the association between pitolisant exposure during pregnancy and subsequent maternal, fetal, and infant outcomes. Participation in the registry is voluntary and participants can withdraw their consent to participate at any time. Data will be collected from enrolled pregnant women and the healthcare providers (HCPs) involved in their care or the care of their infants, if applicable. The registry is strictly observational; the schedule of office visits and all treatment regimens will be determined by HCPs. Only data that are routinely documented in patients' medical records during the course of usual care will be collected. No additional laboratory tests or HCP assessments will be required as part of this registry. The design of this pregnancy registry follows current FDA guidance for designing and implementing pregnancy exposure registries.

Conditions

Interventions

TypeNameDescription
DRUGPitolisantExposure to at least one dose of pitolisant at any time during pregnancy
DRUGComparator ProductsExposure to at least one dose of a comparator product at any time during pregnancy

Timeline

Start date
2021-08-24
Primary completion
2030-06-30
Completion
2030-06-30
First posted
2022-09-10
Last updated
2025-08-05

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05536011. Inclusion in this directory is not an endorsement.