NCT05534893

Effect of Blueberries on Immunity

Immune Benefits of Blueberry Consumption in Overweight Older Men and Postmenopausal Women: A Randomized Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 52 (actual)
• Sponsor: Loma Linda University · Academic / Other
• Sex: All
• Age: 50 Years – 70 Years
• Healthy volunteers: Accepted

Summary

This research study will test the effects of Blueberries on immune functions in overweight older men and postmenopausal women

Detailed description

This study will examine the effects of Blueberries on clinically relevant markers of immune function. Eligible and selected participants will be randomized to one of two groups at the baseline clinic visit. The Blueberry group participants will consume blueberries (2 packets of blueberry freeze-dried powder equivalent to 2 cups of fresh blueberries) added to the habitual diet and the Control group participants will abstain from blueberries (with instructions to limit the consumption of other berries and polyphenol rich foods) but otherwise continue their habitual diet. During the study, clinic visits will occur at 4-week intervals (baseline, weeks 4, 8 and 12) for a total of 4 visits at the Loma Linda University Nutrition Research Center. Blood samples taken at baseline and at week 12 will be assayed for changes in immune function and inflammatory markers.

Conditions

• Immune Response
• Inflammation

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Blueberry powder group	Participants in the blueberry powder group will receive freeze dried blueberries in form of a powder
DIETARY_SUPPLEMENT	Placebo powder group	Participants in the placebo powder group will receive an isocaloric placebo powder

Timeline

• Start date: 2022-10-12
• Primary completion: 2023-09-12
• Completion: 2023-09-12
• First posted: 2022-09-10
• Last updated: 2026-02-04

Locations

1 site across 1 country: United States