NCT05529888

Measure the Serum Level of Homocysteine in Acne Patients Before and After Oral Isotretinoin.

Serum Homocysteine Level in Acne Patients Before and After Oral Isotretinoin

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Aswan University · Academic / Other
• Sex: All
• Age: 15 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

Serum homocysteine level in Acne patients before and after oral Isotretinoin and Correlation between serum level of homocysteine in acne patients before and after Oral isotretinoin treatment

Detailed description

Acne vulgaris is a common chronic inflammatory disease of the skin. It is found in about 80% of young adults and adolescents. It is a disease that affects the pilosebaceous units of the skin and may result in inflammatory or non-inflammatory lesions,Oral isotretinoin (13-cis-retinoic acid) is the only drug that counteracts all the pathogenetic mechanisms that contribute to the development of acne The standard dose of isotretinoin is 0.5 to 1 mg/kg per day for 4 months to a cumulative dose of 120-140 mg/kg is effective in the management of acne vulgaris The scope of our study is to detect serum homocysteine level in acne patient befor and after oral isotrtinoin treatment

Conditions

• Acne Vulgaris

Interventions

Type	Name	Description
DRUG	Isotretinoin	Isotretinoin is a vitamin-A derivative for treatment of moderate to severe acne used in a dose from 20-40 mg for 3 months duration

Timeline

• Start date: 2020-12-15
• Primary completion: 2021-12-15
• Completion: 2021-12-15
• First posted: 2022-09-07
• Last updated: 2022-09-07

Locations

1 site across 1 country: Egypt