NCT05524961

Bright Light Therapy for Non-motor Symptoms in Parkinson's Disease

Randomized Placebo- and Active-controlled Trial for Assessing the Efficacy of Bright Light Therapy for Sleep and Mood Symptoms in Patients With Parkinson's Disease

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 69 (actual)
• Sponsor: Chinese University of Hong Kong · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a randomized placebo- and active-controlled trial for assessing the efficacy of bright light therapy for sleep and mood symptoms in patients with Parkinson's disease

Detailed description

The primary aim of this study is to compare the efficacy of timed-BLT (BLT group) in reducing excessive daytime sleepiness in patients with Parkinson's disease, when compared to a timed-inactivated negative ion generator (active-control group). The secondary aims of the study are to examine the effect of timed-BLT on other non-motor symptoms, including depression, fatigue; and the quality of life. Additional analyses will be carried out to examine the efficacy of the timed-placebo as compared to the random-time placebo (placebo group).

Conditions

• Parkinson Disease

Interventions

Type	Name	Description
DEVICE	Bright light therapy	Regularly-timed exposure to 10,000lux bright light therapy for 60minutes a day for six weeks
DEVICE	Inactivated negative ion generator	Regularly-timed exposure to an inactivated negative ion generator for 60minutes a day for six weeks
DEVICE	Inactivated negative ion generator	Randomly-timed exposure to an inactivated negative ion generator for 60minutes a day for six weeks

Timeline

• Start date: 2022-12-09
• Primary completion: 2025-10-03
• Completion: 2026-01-30
• First posted: 2022-09-01
• Last updated: 2026-03-20

Locations

1 site across 1 country: Hong Kong