NCT05524675

The Effect of Multiple Medications on the Incidence of Organic Dyspepsia

The Effect of Multiple Medications on the Incidence of Organic Dyspepsia：a Prospective Observational Cohort

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 500 (estimated)
• Sponsor: Air Force Military Medical University, China · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Dyspepsia is a very common gastrointestinal disease, presented as predominant symptom of upper abdominal pain. Underlying causes for dyspepsia can classified as organic or functional dyspepsia. Some medications (eg. non-steroid anti-inflammatory drugs (NSAIDs)) were associated with higher frequent incidences of organic lesions. Multiple medications showed an increased trend with aging of the population and multimorbidity. Multiple medications were suggested to be strongly relate to adverse drug events (ADEs), adverse drug reactions (ADRs), drug-drug interactions, and drug-disease interactions, which had been reported to lead to higher incidences of some diseases, including fractures, cognitive impairment and malnutrition. However, it was unknown if multiple medications was associated with more incidences of organic dyspepsia.

Conditions

• Dyspepsia

Timeline

• Start date: 2022-06-01
• Primary completion: 2023-12-31
• Completion: 2024-06-01
• First posted: 2022-09-01
• Last updated: 2022-09-01

Locations

4 sites across 1 country: China