NCT05523336

Pro-ADM vs PCT in Patients With Complications Post Hematopoietic Stem Cell Transplantation

Prospective Non-Interventional Trial to Evaluate Kinetics, Diagnostic and Prognostic Value of Pro-ADM as Compared to PCT in Patients Presenting With Infections or Other Complications Post Hematopoietic Stem Cell Transplantation (HSCT)

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: Azienda Ospedaliera Ospedale Infantile Regina Margherita Sant'Anna · Academic / Other
• Sex: All
• Age: 28 Days – 39 Years
• Healthy volunteers: Not accepted

Summary

Prospective, multicenter, spontaneous, non-interventional, non pharmacological. Study aimed at evaluate kinetics, diagnostic and prognostic value of pro-ADM (proadrenomedullin) as compared to PCT (procalcitonin) in patients presenting with infections or other complications post hematopoietic stem cell transplantation (HSCT)

Detailed description

Evaluation of diagnostic performance of pro-ADM as compared to palliative care therapy (PCT) in paediatric and young adult patients with any type of complications after hematopoietic stem cell transplantation or with transplant related complications.

Conditions

• Stem Cell Transplant Complications

Interventions

Type	Name	Description
OTHER	observation	observation and prospective data collection

Timeline

• Start date: 2022-10-20
• Primary completion: 2024-09-01
• Completion: 2025-03-01
• First posted: 2022-08-31
• Last updated: 2023-05-25

Locations

1 site across 1 country: Italy