NCT05520021

The Treatment of Magnesium Sulfate and Nifedipine in Preterm Labor Threat

Comparison of the Effects of Nifedipine and Magnesium Sulfate on Maternal and Fetal Doppler Blood Flow Patterns in Women With Preterm Labor

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Konya Meram State Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 38 Years
• Healthy volunteers: Accepted

Summary

Comparison of the effects of Nifedipine and MgSO4 therapies on maternal and fetal blood flow.

Detailed description

In this study, the investigators aim to compare the effect of Nifedipine and MgSO4 therapies on Doppler parameters of the uterine, umbilical, middle cerebral arteries, and ductus venous in the first 48 hours of therapy in pregnancies with preterm labor threat and also compare perinatal outcomes after delivery between the groups.

Conditions

• Preterm Labor Without Delivery
• Pregnancy Preterm

Interventions

Type	Name	Description
DRUG	Nifedipine	A total of 30 pregnancies with preterm labor threats will be treated with Nifedipine.
DRUG	Magnesium sulfate	A total of 30 pregnancies with preterm labor threats will be treated with Magnesium sulfate.

Timeline

• Start date: 2022-09-01
• Primary completion: 2022-12-31
• Completion: 2023-03-31
• First posted: 2022-08-29
• Last updated: 2022-09-15

Locations

1 site across 1 country: Turkey (Türkiye)