NCT05519345

Operant Conditioning After ACL Reconstruction

Conditioning Brain Responses for Modulating Corticospinal Excitability After ACL Reconstruction

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 22 (actual)
• Sponsor: University of Michigan · Academic / Other
• Sex: All
• Age: 14 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to examine if the changes in corticospinal function that accompany ACL reconstruction can be improved through a form of mental coaching and encouragement, known as operant conditioning.

Detailed description

It is theorized reduced corticospinal excitability contributes to quadriceps dysfunction after knee injury and joint disease. Current rehabilitation does not directly target the alterations in corticospinal excitability, which may limit recovery. Operant conditioning is an emerging approach capable of increasing corticospinal excitability by directly targeting the corticospinal pathways. However, it remains to be determined whether operant conditioning of the corticospinal pathway may improve corticospinal function after knee trauma. Therefore, this study will evaluate the ability of operant up-conditioning of the corticospinal pathway to improve corticospinal function after ACL reconstruction.

Conditions

• Anterior Cruciate Ligament Injuries

Interventions

Type	Name	Description
BEHAVIORAL	Operant Conditioning	Active encouragement and feedback to increase motor evoked response during stimulation.
BEHAVIORAL	Control	Absence of active encouragement and feedback to increase motor evoked response when stimulated.

Timeline

• Start date: 2022-12-28
• Primary completion: 2023-10-10
• Completion: 2023-10-10
• First posted: 2022-08-29
• Last updated: 2024-01-23

Locations

1 site across 1 country: United States