NCT05519007

Rate of Total Joint Infection 90-day After Surgery Following Irrigation With Next Science No-Rinse Solution vs SOC Alone

Clinical Evaluation of the Rate of Total Joint Infection 90-day After Surgery Following Irrigation With Next Science No-Rinse Solution vs SOC Alone

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 936 (estimated)
• Sponsor: Northwell Health · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

A prospective, single-site, double-arm, parallel, interventional, randomized, controlled clinical trial to assess 90-day rate of joint infections in subjects undergoing primary hip replacements after administration of Next Science No-Rinse Solution (hereby referred to as NS) vs SOC (saline irrigation). The Next Science treatment arm will exhibit greater reduction in rate of 90-day post-operative joint infection than SOC (saline) arm

Conditions

• Joint Infection

Interventions

Type	Name	Description
OTHER	No-Rinse Solution (NS)	The surgical site will be irrigated with NS prior to closure,
OTHER	Saline irrigation	The surgical site will be irrigated with Saline

Timeline

• Start date: 2023-09-26
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2022-08-29
• Last updated: 2025-05-23

Locations

3 sites across 1 country: United States