Trials / Completed
CompletedNCT05517122
Effect of Oral NAD+ Precursors Administration on Blood NAD+ Concentration in Healthy Adults
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 68 (actual)
- Sponsor
- Société des Produits Nestlé (SPN) · Industry
- Sex
- All
- Age
- 18 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
Nicotinamide adenine dinucleotide (NAD) is a coenzyme playing a central role in human metabolic pathways. A recognized approach to increase NAD level is through oral supplementation of its precursors promoting NAD synthesis in vivo. NAD precursors exist in multiple forms. However, it is unclear how the various precursors compare in their ability to increase NAD levels in human blood. The purpose of this study is to compare the effect of 3 NAD precursors on whole blood NAD metabolome.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Nicotinamide (NAM) | 500 mg a day |
| DIETARY_SUPPLEMENT | Nicotinamide Riboside (NR) | 1000 mg a day |
| DIETARY_SUPPLEMENT | Nicotinamide Mono Nucleotide (NMN) | 1000 mg a day |
| DIETARY_SUPPLEMENT | Microcrystalline cellulose | 500 mg a day |
Timeline
- Start date
- 2022-07-12
- Primary completion
- 2022-11-24
- Completion
- 2022-11-24
- First posted
- 2022-08-26
- Last updated
- 2025-04-24
Locations
1 site across 1 country: Switzerland
Source: ClinicalTrials.gov record NCT05517122. Inclusion in this directory is not an endorsement.