NCT05516953

Baclofen in Preventing Postoperative Nausea and Vomiting After Bariatric Surgery

Clinical Study Evaluating the Efficacy of Baclofen in Preventing Postoperative Nausea and Vomiting After Laparoscopic Sleeve Gastrectomy

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Tanta University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

This study aims to evaluate the possible efficacy of baclofen on postoperative nausea and vomiting in patient with morbid obesity who will undergo laparoscopic sleeve gastrectomy.

Detailed description

. A total of 100 morbidly obese patients who will be scheduled for sleeve gastrectomy will be included in the study. The patients will be selected from those attending Gastrointestinal and Laparoscopic Surgery Unit, General Surgery Department, Tanta University Hospital, Tanta, Egypt. The participants will be randomized into four groups by closed envelop method

Conditions

• Postoperative Nausea and Vomiting
• Laparoscopic Sleeve Gastrectomy
• Morbid Obesity

Interventions

Type	Name	Description
DRUG	Baclofen Tablets	10 mg oral baclofen 1 h before anesthesia

Timeline

• Start date: 2022-08-22
• Primary completion: 2024-12-28
• Completion: 2025-02-28
• First posted: 2022-08-26
• Last updated: 2025-04-22

Locations

1 site across 1 country: Egypt