NCT05515913

Nutritional Status and ASD Severity of Autistic Spectrum Disorder Children in Addis Ababa, Ethiopia; Case Control Study

Assessment of Nutrient Profile, Nutritional Status, Development and Severity of Children With Autistic Spectrum Disorder in Comparison With Typically Developing Children in Addis Ababa, Ethiopia

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 52 (actual)
• Sponsor: Addis Ababa University · Academic / Other
• Sex: All
• Age: 4 Years – 18 Years
• Healthy volunteers: Accepted

Summary

The study conducts a case control analysis of the nutritional status and intake of autistic spectrum disorder diagnosed children as compared to typically developing children in Addis Ababa, Ethiopia. It included analysis of anthropometric measurements, three days food diary food intake, urinary iodine analysis, childhood autism rating scale diagnosis, food frequency and eating behavior questioner and proximate analysis of one day major meals of selected subjects.

Detailed description

Sample population was Addis Ababa city in which subjects were selected from one of the two autism centers in the country. Random sampling method was applied to select subject from the total enrolled children in the center using Ryan 2013 sample size calculation formula. Subjects already diagnose with autistic spectrum disorder that didn't have any other chronic disease that affect diet and nutrition were included in the study. Subjects were selected randomly from each grade level in the center. They were registered and taken for data collection. Sample and Data was collected with the help of each child's center caregiver and parent. Childhood autism rating scale diagnosis, eating behavior analysis were analyzed for the ASD and anthropometric indices Z scores, urine iodine concentration, three days food diary analysis, major meals proximate analysis, food frequency and dietary diversity was assessed and compared to typically developing children in Addis Ababa. Data entry and analysis was conducted using Emergency Nutrition Assessment software, Microsoft excel and Statistical Package for the Social Sciences software.

Conditions

• Autistic Spectrum Disorder

Interventions

Type	Name	Description
OTHER	Nutritional status	Nutritional status of children as analyzed by anthropometric indices was under study
BEHAVIORAL	Eating behavior	The eating behavior of ASD children as analyzed by frequency of refusal of new food, sensitivity to food, food allergy and gastrointestinal systems was under study
OTHER	Urine iodine concentration	the 24 urine iodine concentration of all subjects was under study
OTHER	Nutrient intake	The nutrient intake as analyzed by three days food diary and major meal proximate analysis of subjects was under study
OTHER	Dietary assessment	The food frequency and dietary diversity of all subjects as analyzed by food frequency questioner, dietary diversity score and food variety score was under study
OTHER	Childhood autism rating scale	The autistic severity of ASD diagnosed children was under study as analyzed by childhood autism rating scale diagnosis

Timeline

• Start date: 2021-08-14
• Primary completion: 2021-11-23
• Completion: 2022-02-08
• First posted: 2022-08-25
• Last updated: 2022-08-25

Locations

1 site across 1 country: Ethiopia