Trials / Completed
CompletedNCT05514197
The Impact of Intravenous Vitamin C Combined With Nerve Blocks on Postoperative Pain and Recovery After Total Knee Arthroplasty
The Impact of Intravenous Vitamin C Combined With Nerve Blocks on Postoperative Pain and Recovery After Total Knee Arthroplasty.
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 73 (actual)
- Sponsor
- Chimei Medical Center · Academic / Other
- Sex
- All
- Age
- 50 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
The aim of this prospective randomized-control study was to evaluate the impact of a single high-dose intravenous vitamin C added to ultrasound-guided blocks at induction on postoperative pain, sngception and early functional rehabilitation of the knee joint in patients under-going total knee arthroplasty.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Ascorbic acid 100mg/kg, Maximus 10g | Intravenous loading of 100mg/kg ascorbic acid with normal saline, totally 100ml Completed before induction |
| DRUG | Control Rx | Intravenous loading 100ml normal saline |
Timeline
- Start date
- 2022-11-02
- Primary completion
- 2023-12-13
- Completion
- 2024-01-11
- First posted
- 2022-08-24
- Last updated
- 2025-11-19
Locations
1 site across 1 country: Taiwan
Source: ClinicalTrials.gov record NCT05514197. Inclusion in this directory is not an endorsement.