NCT05513014

Impact of Secukinumab on Clinical and Patient Reported Outcomes in Patients With Psoriasis

Impact of Secukinumab on Clinical and Patient Reported Outcomes in Patients With Psoriasis in a Real World Setting in the US (Bionaive Secukinumab Users NVS 521)

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,518 (actual)
• Sponsor: Novartis Pharmaceuticals · Industry
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

The study was conducted to describe the demographics, disease characteristics, disease severity, comorbidities and patient reported outcomes at baseline and follow-up periods among adult patients diagnosed with PsO in CorEvitas' PsO Registry under routine medical care initiating secukinumab (SEC).

Detailed description

This is a retrospective analysis of a prospective observational cohort using CorEvitas' PsO registry of adult PsO patients. This study describes clinical and patient reported outcomes among adult patients initiating Secukinumab (SEC). Biologic experienced and naïve patients are examined separately. This study also describes changes in clinical and patient reported outcomes over time. CorEvitas' Psoriasis Registry is a prospective, observational cohort of adult PsO patients starting systemic therapy, launched in April 2015 with sites in the US and Canada. Data collection occurs every \~6 months at routine dermatology visits. This study included US PsO patients who initiated secukinumab at or after enrollment and had a subsequent 6- and/or 12-month follow-up visit (Apr 2015 to Dec 2020).The index date is defined as the date of the first SEC initiation at or after enrollment.

Conditions

• Psoriasis

Interventions

Type	Name	Description
DRUG	Secukinumab	Patients with Psoriasis who initiated Secukinumab

Timeline

• Start date: 2021-03-21
• Primary completion: 2021-08-31
• Completion: 2021-08-31
• First posted: 2022-08-23
• Last updated: 2022-11-08

Locations

1 site across 1 country: United States